Senior Scientist (Molecular Biology & Discovery)
Posted on: January 16, 2022
We are a rapidly expanding and well-funded biotechnology company
focused on employing cutting edge protein engineering and
multi-specific antibodies to discover therapeutic solutions to
challenging diseases. At Invenra, we start with biology, then
employ our extensive technology toolbox and efficient discovery
engine to design and create first- and best-in-class drug
candidates. Using our proprietary B-BODY -, SNIPER - and CLUSTR -
technologies, we have generated a robust pipeline of
next-generation multi-specific antibodies to address unmet
therapeutic needs in immuno-oncology and autoimmunity. Invenra's
employee-focused management and flexible work environment creates a
culture of energy and innovation where everyone makes a difference,
and everyone benefits from success. For more information, please
Invenra is seeking an enthusiastic Senior Scientist with a strong
background in cutting-edge Molecular Biology and antibody library
building. As part of the Discovery group, the successful applicant
will work cross-functionally with Discovery and Protein Engineering
to improve our process and throughput, develop next generation
libraries, and continually improve our bispecific platform.
Design and perform molecular biology experiments, oversee their
execution, and interpret/communicate results effectively to the
team in meetings.
Actively involved in optimizing nucleic acid manipulation from
single cells in collaboration with our innovation team.
Perform laboratory procedures following SOPs that includes DNA
extraction, cloning, mRNA isolation, cDNA synthesis, PCR and Next
Coordinate molecular biology research activities with scientists
specializing in other fields (Cell Biology and Protein
Support the development, application, and optimization of DNA
constructs for genetic modification of cell lines.
Evaluates new molecular biology technologies to enhance or
complement our current research.
Maintain laboratory notebooks and assist in drafting SOPs and
preparing workplans, reports, manuscripts, and presentations.
Required Education, Experience, and Competencies:
M.S., or Ph.D. in biochemistry, molecular and cellular biology,
immunology, or related area AND 3+ year experience (M.S.) or 10+
years' experience (B.S.) in relevant industrial or academic
Experience developing/optimizing protocols for nucleic acid
cloning, amplification, modification, and expression analysis.
Working knowledge of vector design for gene expression, genetic
reporter systems and genome engineering applications - background
in phage/yeast display biology will be considered as a plus.
Experience optimizing/developing protocols for DNA assembly and
library constructions for applications such as protein engineering,
mRNA and/or phage display is a plus.
Basic knowledge of the DNA analysis software such as SnapGene is a
Some Familiarity with stem cell tissue culture and phage and yeast
display platforms is a plus.
Experience in ddPCR or other emulsion-based strategies is a
Experience building and running selections on biomolecular
Proven ability to design well-controlled experiments.
Strong team player with good communication skills.
Preferred but not required:
General knowledge of immunology and antibody structure-function
relationship is a plus.
Note: All job candidates must be authorized to work in the United
Include a competitive compensation and benefits package composed of
health and dental benefits, 401k match, stock option grants, PTO,
tuition reimbursement, a generous bonus plan and relocation
assistance. At Invenra, we believe in maintaining the highest
ethical standards and ensuring that all employees have a good
Invenra is an Equal Opportunity Employer. Invenra is committed to a
diverse workforce. We believe every individual brings their own
unique experience, and these experiences foster innovation and
success. We are enthusiastically inclusive of age, race, creed,
color, disability, marital status, sex, national origin, ancestry,
sexual orientation, and military service.
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Keywords: Invenra, Madison , Senior Scientist (Molecular Biology & Discovery), Other , Madison, Wisconsin
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