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Associate Scientist, CMC

Company: Arrowhead Pharmaceuticals
Location: Madison
Posted on: March 29, 2020

Job Description:

The Position:
Arrowhead Pharmaceuticals is seeking a highly motivated individual to become a part of its scientific team. We have an immediate opening for an Associate Scientist to work as a Chemist in the Chemistry, Manufacturing, and Controls Group focusing on oligonucleotide synthesis development. This is an ideal position for an individual with an organic or biological chemistry background who has an interest in projects related to novel technology in synthesis and purification of oligonucleotides and bioconjugates. The successful candidate will be expected to:


  • Work closely with senior chemists on development of new synthetic approaches to desired compounds with an eye toward large-scale synthesis
  • Cooperate with other chemists in the group in preparation of complex organic constructs
  • Perform solid-phase synthesis and purification of oligonucleotide drug candidates
  • Analyze small-molecule and macromolecular targets using standard methods
  • Maintain a well-documented laboratory notebook
  • Track progress against project timelines, generate regular status updates, and communicate progress and issues to management, including presentation of findings at team meetings
  • Coordinate delivery of materials both internally and externally

    Requirements:

    • BS (minimum 3 years of relevant laboratory experience) or MS in chemistry or biochemistry with an excellent understanding of organic and analytical chemistry
    • Experience with synthetic organic chemistry
    • Excellent verbal and written communication skills
    • Experience with small-molecule and macromolecule analytical techniques (e.g., HPLC, UV-Vis spectrophotometry, mass spectrometry, NMR, etc.)
    • Strong problem-solving skills
    • Eagerness to learn new techniques

      Preferred:

      • Experience working with both small molecule and large molecule synthetic targets either in an academic or industrial setting
      • Experience with solid phase synthesis of oligonucleotides or peptides
      • Experience in nucleotide synthesis
      • Basic familiarity with GLP/GMP regulations


        Please submit a resume and cover letter to careers@arrowheadpharma.com.
        Arrowhead provides competitive salaries and an excellent benefit package.
        All applicants must have authorization to work in the US for a company.

Keywords: Arrowhead Pharmaceuticals, Madison , Associate Scientist, CMC, Other , Madison, Wisconsin

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